Role:To execute activities related to R&D Peptide Process Development & Scale-ups, along with a group comprising of Research Officers/ Research Assistants in co-ordination with Team/Group LeaderDetails of Previous Work Experience (Mandatory Requirement)
Literature search and ROS (Route of Synthesis) finalization
Basic knowledge of Orthogonal protected amino acid and Peptide
Handling of hazardous chemical like Trifluoroacetic acid
Knowledge of handling of analytical HPLC/Oligo Synthesis
Purification using Preparative HPLC
Preparative column packing and usage.
Computer literacy etc.
Knowledge of Phosphoramidalin /handling/storage
Job Description:● Literature search with respect to assigned project and finalizing the non-infringing synthetic route● Experimentation (Process development, DoE study, optimization and validation).● Purification of Peptide and knowledge of lyophilisation of pure solution.● Handling of analytical HPLC and preparation of buffer.● Characterisation of Peptide using HRMS,2D NMR, IR, Peptide mapping and sequencing.● Preparation of Technology transfer documents.● Scaling-up of process developed at R&D.● Assisting to RA in filing DMF.● General Laboratory Management etc.
